Microarrays, including genome tiling microarrays, are exceptionally powerful tools for querying diverse genomic features, including mapping gene expression and structure, analyzing polymorphisms, ...

Let us compare the two competing approaches to gene selection in a simulation experiment where the true answer is known. We will treat them solely as ranking procedures with the length of the gene ...

This is a preview. Log in through your library . Abstract Selection of significant genes via expression patterns is important in a microarray problem. Owing to small sample size and large number of ...

Relationship of pro-angiogenic factor Cyr61to colorectal cancer development and prognosis. Background: Microarrays are widely used to study gene expression patterns in cancer. In colorectal cancer, it ...

San Diego, Ca. -- Researchers at the University of California, San Diego have used a new strategy to identify differences between non-metastatic and highly metastatic breast cancer cells. The article ...

This is a preview. Log in through your library . Abstract Regulation of gene expression through translational control is a fundamental mechanism implicated in many biological processes ranging from ...

MicroRNAs (miRNAs) are small, short non-coding RNAs that bind to specific messenger RNAs (mRNAs) and regulate gene expression either by degradation or by translational inhibition of the mRNA. miRNAs ...

Small molecule microarrays allow screening of biomolecules such as peptides and carbohydrates. By immobilizing these small molecules on a microarray, interactions can be quickly assessed through a ...

Curious about how to detect and characterize tumor-derived biomarkers from liquid biopsy samples? Genomics-based methods now provide access to more molecular data than ever before, delivering cancer ...

Early Completion of Model-Assisted Designs for Dose-Finding Trials Accurate assessment of a molecular classifier that guides patient care is of paramount importance in precision oncology. Recent years ...

Many recently developed pneumococcal serotyping methods detect the dominant serotype in a laboratory or field sample, but several fail to detect minor serotypes, according to a study published this ...