Mitochondria produce most of the cellular ATP by the process of oxidative phosphorylation (OXPHOS) and generate most of the endogenous oxygen radicals as a toxic by-product. In addition, mitochondria ...

Most pharmaceuticals sold today have their origin in a biochemistry laboratory. Drug discovery has traditionally started with a biochemical pathway implicated in a pathophysiological process. An ...

BUFFALO, N.Y. -- A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

DNA microarray chips enable the parallel investigation of a given sample concerning the presence and amount of specific DNA sequences within that sample. Whereas today such chips utilize optical ...

This is a preview. Log in through your library . Biometrics is a scientific journal emphasizing the role of statistics and mathematics in the biological sciences. Its object is to promote and extend ...

Determining true HER2 status in breast cancers with polysomy using alternative chromosome 17 reference genes: Implications for trastuzumab therapy. Background: Systemic chemo- and chemoradiation ...

Reported Data Supports the Potential Extension of HD-MAP Vaccine Delivery to Oncology Indications Recently published data generated by researchers at The University of Queensland and Vaxxas shows ...

Hitachi Software Engineering Co. Ltd. and a Japanese venture DNA Chip Research Inc. have jointly developed DNA (deoxyribonucleic acid) chips that carry about the same number of genes as the full human ...